- University of Colorado (Aurora, CO)
- …of pluripotent stem cells into a variety of cell types, and CRISPR-Cas9-mediated gene targeting . Laboratory duties will involve receiving laboratory reagents and ... including melanoma and other skin cancers, and development of approaches to gene therapy in the skin. The Dermatopathology unit provides pathology services to… more
- Children's Mercy Kansas City (Kansas City, MO)
- …of the developing lung. Specific expertise in endothelial/vascular biology, Crispr/Cas9 gene targeting , use of single cell RNA-sequencing and bioinformatics ... and rodent work in the lung is preferred. Minimal requirements include a PhD degree with 3-5 years of post-graduate experience. The qualified applicant will work as part of a vibrant team consisting of physician-scientists, research technicians and PhD… more
- Sandia National Laboratories (Livermore, CA)
- …using various CRISPR systems to alter gene expression through genome editing, gene activation or mRNA targeting tools. The selected candidate will continue ... genomics assays using several types of CRISPR screens (eg knockout, activation, mRNA targeting ) + Develop cell reporter assays + Design viral vectors for in vivo… more
- Memorial Sloan-Kettering Cancer Center (New York, NY)
- …current funded projects exploring modifiers of penetrance of germline homologous repair gene variants, targeting of inherited nucleotide repair deficiency, and ... developing of neo-antigen vaccines for syndromes associated with replication repair deficiencies , for example. C ross-departmental collaborative programs that provide opportunity for growth include the young adult population through the the Lisa and Scott… more
- Bio-Techne (Minneapolis, MN)
- …will help develop and execute the commercial product strategy for Cell and Gene Therapy (CGT) products within Bio-Techne that offer significant promise to treat life ... of experience** + **Must have experience and understanding of the Cell and Gene Therapy market** + **Strong business acumen and aptitude for customer requirements**… more
- Lilly (Indianapolis, IN)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with an experience in developing… more
- Lilly (Indianapolis, IN)
- …includes active investments in Oligonucleotide development, nanomedicines for tissue specific targeting and other gene delivery strategies. The drug product ... team is also investing in building new platforms to support complex formulations such as lipid nanoparticles, Antibody Drug Conjugates and AAV and other non-viral vector delivery. We are seeking highly motivated professionals with extensive experience in… more
- Pfizer (Groton, CT)
- …bring innovative approaches to tackle complex protein and RNA biology and diverse targeting modalities. As part of this early discovery group, the individual will ... small molecule mechanism of action. The successful candidate will integrate gene editing methods with high-dimensional functional assays and physiologically relevant… more
- Rush University Medical Center (Chicago, IL)
- …will lead research efforts on human iPSC-based disease modeling or/and CRISPR gene perturbations. The job will perform experiments, analyze data, compile results, ... brain organoid cultures, high-content imaging, molecular biology, viral packaging, CRISPR gene perturbations and data analysis. Exemplifies the Rush mission, vision… more
- Editas Medicine (Cambridge, MA)
- …allowing us to harness the power and potential of CRISPR/Cas9 and CRISPR/Cpf1 (Cas12a) gene editing. We believe our people are at the core of everything we do, ... must have a proven track record in the discovery and development of drugs targeting diseases of non-CNS/peripheral tissues at least through IND, with more than one… more
- UCLA Fielding School of Public Health (Los Angeles, CA)
- …analyze data and lead projects in vascular biology, focusing on high-resolution gene expression profiling techniques. Responsibilities: + Collaborate with the PI and ... the lab. + Conduct innovative research in vascular biology, specifically targeting intracranial artery disease. + Utilize techniques like western blotting, qPCR,… more
- Stanford University (Stanford, CA)
- …sequencing data, deconvolute bulk sequencing datasets, and perform differential gene expression analyses; maintain detailed records of pipelines, workflows and ... sequencing data to identify promising peptide-MHC target antigens for immunotherapeutic targeting , maintain detailed records of pipelines, workflows and outcomes. +… more
- Regeneron Pharmaceuticals (Cambridge, MA)
- …contract lab testing and supporting safety testing for novel drug products targeting oncological indications and providing oversight for the testing of release, ... years of relevant experience. Biopharmaceutical/industry experience in the cell and gene therapy space is strongly preferred. Must have experience with environmental… more
- University of Rochester (Rochester, NY)
- …coordination and execution of experiments to establish the function and therapeutic targeting of various oncogenes of interest in myeloid leukemia to the principal ... immunohistochemistry. + Animal experiments, breeding and maintenance of wild-type and gene specific knockout mice under development. Xenografting cancer cells in… more
- Emory Healthcare/Emory University (Atlanta, GA)
- …for mRNA and other RNA-based drugs. The drugs may consist of vaccines, gene replacement therapies, mRNA-encoded antibodies, CRISPR gene editing therapies, and ... programs will be on extrahepatic delivery, and will therefore require both de- targeting the liver and increasing delivery to other tissues. Prepares and publishes… more
- University of Washington (Seattle, WA)
- …on the development, characterization, and refinement of vaccines and therapeutics targeting infectious diseases and cancers. This position will support projects ... Mouse handling, injections (IM, SQ, IP, RO), ear punching, vaccinations ( Gene Gun, IM, Intranasal, among other routes), challenge inoculations (influenza,… more
- University of Utah (Salt Lake City, UT)
- …keratan sulfates. * Chemical tools for studying and therapeutically targeting phosphorylation-dependent cellular signaling pathways. * Medicinal chemistry and ... biology targeted toward enzymes involved in immunology, neurological development, cancer, gene regulation, etc. * New tools for studying the biosynthesis,… more
- University of Colorado (Aurora, CO)
- …of our studies is to identify mechanisms of resistance to therapies targeting these pathways. The postdoctoral fellow will use unbiased approaches, including ... world, that have been molecularly characterized by genome-wide copy number and gene expression, histology, and mutations. Together, these tools and approaches will… more
- Burns & McDonnell (Columbus, OH)
- …and knowledge of life sciences markets and processes (fermentation, cell / gene therapy, API, blood products, purification, fill / finish, medical devices, etc) ... critical project objectives + Own the development of direct reports including targeting work for individual team members to expand their capabilities + Stay… more
- UT Health (Houston, TX)
- …projects cover fundamental mechanistic studies and the design of therapeutics targeting significant human diseases, such as viral infections, cancer, and ... crucial areas of biomedical research.** **Molecular Biology, such as PCR and gene cloning; Biochemistry, such as protein purification and affinity measurement; Cell… more